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Consequently, claims about clinical benefit should be made cautiously and framed as hypothesis-generating rather than definitive (154, 156)

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The Reciprocal Interaction Between Gut Microbiota (GM) and Pharmacological Therapies in Parkinson Disease (PD) The initial symptomatic treatments of early motor PD rely on oral pharmacological therapies, such as levodopa, long-acting dopamine agonists, or monoamine oxidase type B inhibitors (MAO-BI)