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Deletions were confirmed via PCR using primers in the regions upstream and downstream of the targeted gene, primers within the Orf, and primers with homology to the respective healing fragments

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HbA1c values attained a plateau in the 2 groups of patients receiving CagriSema and semaglutide at 20 weeks, whereas in the cagrinlitide group the decrease in HbA1c was more gradual and was progressive up to the end of treatment at 32 weeks [10]

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