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The antiproliferative, antioxidant, and anticarcinogenic effects of GSPs can be explained, principally, by their action on decreasing expression of NF-κB targeted genes [85], [165], [166]
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8,9 Conversely, a healthy microbiome, through its production of antioxidant metabolites, modulation of immune responses, and stimulation of antioxidant response elements (AREs) can help maintain redox equilibrium, showcasing the potential of microbiome-based interventions in restoring health
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