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This isoform is known to catalyze the N-glucuronidation of primary, secondary and tertiary amines, among those are anticonvulsivants, tricyclic antidepressants and antipsychotics, such as lamotrigine, doxepin or clozapine (Li et al., On the other hand, the UGT2B7 isoform catalyzes the glucuronidation of morphine to 3-O- and 6-O-glucuronide, the latter metabolite presenting a higher analgesic potency than morphine (Gong et al., 2)
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