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High-dose dandelion extract has been shown to increase the expression of Nrf2 (the master regulator of antioxidant genes) in the liver, and the protein expression of Nrf2 target gene HO-1 in the liver is dose-dependent, leading to a better activation of the Nrf2 signaling pathway and suppression of oxidative stress [158]

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Effective therapeutics for DMD remain limited despite urgent, unmet clinical needs