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“In clinical trials, LGD-4033 significantly increased lean body mass without adverse androgenic effects,” Basaria et al., Journal of the American Geriatrics Society
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3.1.1 Nuclear receptor signaling disruption 3.1.1.1 Androgen receptor antagonism Bisphenol A exhibits androgenic antagonism, functioning as a competitive antagonist that blocks androgen receptor binding and subsequently reduces ARE-mediated gene transcription, with documented effects on androgen-dependent gene expression
