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Sheet A · Product board
Unit price
USD21.07
USD54.07

Pay in 4 interest-free payments of $5.27 Learn more

Field rating
4.5

Verified studio score · Spec revision current

Fit · Size
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SKU: 94557494379

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Ships within 48 hours · Estimated delivery Nov 9 - Nov 14

Description

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Work by Walsh and Clardy showed that the two amide bonds are constructed by an NRPS-independent pathway including an ATP-grasp enzyme DdaF and an ABS DdaG (Supplementary Fig

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This reaction weakens the binding between Keap1 and NRF2, allowing NRF2 to escape the negative regulation of Keap1 and avoiding ubiquitination and degradation

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