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[223] demonstrated that the intraperitoneal administration of SR9009, another REV‐ERB agonist, prevents osteoclast differentiation and bone resorption, resulting in inhibited ovariectomy‐induced bone loss in mice [223]

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Figure 1 2.2 Fundamental concepts and molecular mechanisms of ferroptosis Ferroptosis was first described by Dixon in 2012 as an iron-dependent form of cell death featuring uncontrolled lipid peroxidation