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Neuronal HDAC9 overexpression mitigates cognitive and synaptic deficits in 5xFAD mice To assess whether overexpression of HDAC9 could ameliorate cognitive and synaptic deficits in 5xFAD mice, we crossed HDAC9-Tg flox-STOP-flox mice with 5xFAD mice to generate 5xFAD/HDAC9-Tg flox-STOP-flox , 5xFAD and WT offspring (Fig
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(1995) found no significant differences, and Hernanz et al
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