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According to these studies, the transmembrane tyrosine kinase receptor of mononuclear cells, colony stimulating factor 1 receptor, is an important regulator of macrophage polarization ( Macrophages and CKD Macrophages - obesity and diabetes The link between obesity, insulin resistance and type 2 diabetes is well known ( Obese people are characterized by severe adipose tissue inflammation, insulin resistance and glucose intolerance
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