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Our results showed that the differential metabolites in patients with rosacea were mainly enriched in pathways related to metabolism and biosynthesis of various amino acids (such as alanine, aspartate, glutamate, arginine, proline, valine, leucine, and so on) and aminoacyl-tRNA biosynthesis, in which the alanine, aspartate, glutamate metabolism pathway was highlighted (Figure 2A)