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Dysregulation of these receptor pathways has been implicated in various neuropsychiatric and neurodegenerative conditions, including sleep disturbances, anxiety, and depression [4]

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Research shows that creatine has a multifaceted mechanism, boosting brain energy metabolism, modulating neurotransmitter systems, and providing neuroprotection, especially when combined with antidepressants at a dose of 4-5 g/day for two to eight weeks