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Initiation of Pro-Survival Signaling ERK Pathway Activation NAC activates the Ras-extracellular-signal-regulated kinase (ERK) pathway, which is crucial for neuroprotection against amyloid-beta (Aβ) toxicity

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As shown in Figure 4A, iron content was dramatically elevated in the UUO group compared with that in the sham group, which was effectively decreased after DSI intervention (Figure 4A)