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Frontiers | Natural products for the treatment of allergic rhinitis: focus on cellular signaling pathways and pharmacological targets

Although metalloregulator engineering and rational or targeted mutagenesis campaigns geared toward biosensor applications have provided valuable new information on how transition metal selectivity emerges, we believe nonguided design paths such as directed evolution or more recent “ligand-aware” artificial intelligence tools may ultimately emerge as the new standard approach for biosensor development

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