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Therefore, the lysis of greater than ∼0.2% of the RBC volume, whether in benchtop experiments or in vivo , could liberate enough ATP to mimic (or mask) that resulting from regulated, non-lytic release, depending on such additional variables as hematocrit, PO 2 , and the presence of ectonucleotidases (ATPases) (Kirby et al., 2015
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