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In silico, they determined that ATOX1 p.G14S would be located in a copper-binding motif, which may negatively interfere with the binding of ATOX1 to the MBD4 domain of ATP7B for copper transfer
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Merck KGaA Headquarters: Darmstadt, Germany Merck KGaA is globally recognized for manufacturing specialty chemicals, life science products, and advanced chromatography solutions for pharmaceutical and biotechnology applications
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