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However, small donor sample sizes limit generalizability, as they may not capture donor-dependent shifts or reflect broader diversity in age, diet, or health

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Additionally, Chatzistergos (2024) showed that the Hoyt and Schatten (1993) model conflicts particularly with the ACRIM composite by exhibiting opposite trends during the so-called ACRIM-gap, making Scafetta’s extension of Hoyt and Schatten (1993) with ACRIM invalid

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