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How does metformin (biguanide oral hypoglycemic agent) cause vitamin B12 deficiency?

Since its discovery in the early 1990s, BPC-157 has been studied extensively in laboratory and animal models for its potential influence on cellular protection, structural repair, and angiogenic processes

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Using epithalin to combat some of the neurodegeneration and things like retinitis pigmentosa, downstream neurodegeneration in rp, which is a very common, unfortunately blinding disease, or even in glaucoma