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Through co-immunoprecipitation (CO-IP) experiments, we discovered that FOXO4-DRI prevents the binding of FOXO4 to P53, facilitating the phosphorylated P53 nuclear exclusion, which subsequently trigger BAX and cleaved caspase-3, leading to the apoptosis of senescent cells

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Recent studies suggest that the fruit, bark, leaves, and roots of amla significantly reduce plasma glucose levels through the inhibition of α-amylase and α-glucosidase activity and activation of the AMPK signaling pathway