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l INDICATIONS AND DOSE Opioid-induced constipation when response to laxatives inadequate l ▶ Rizmoic (Shionogi BV) A Naldemedine (as Naldemedine tosylate) 200 microgram Rizmoic 200microgram tablets | 28 tablet P £41.72 l CONTRA-INDICATIONS Gastro-intestinal or peritoneum malignancy (risk of gastro-intestinal perforation)
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