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The role of S1PR2 appears highly context-dependent, potentially exerting opposing effects in different tissues or disease states ( In summary, S1PR2 adds another layer of complexity to BA signaling within the TIME, potentially acting as a receptor for conjugated BAs to influence cancer cell invasiveness and inflammation, possibly contributing to a pro-tumorigenic microenvironment in certain settings
Global Health
Pack Size:100 G / 3.5 Oz
Histopathology includes lobular inflammation with lymphocytic–histiocytic infiltration, scattered apoptotic necrosis, architectural disorganization, and—when sustained—periportal/perilobular fibrosis [18]
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