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A recent study used approximately 40,000 participants’ data from the United States National Health and Nutrition Examination Survey from 1999 to 2021 as representative of the US population
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After the model was expanded to include GS-H 2 Q adduct formation as a function of its reduction potential, it was then combined with the Reed glutathione model 21 in order to simulate how the quinone redox-metabolism of doxorubicin influenced the glutathione metabolism
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