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DMSO applied in a wide range of concentrations from 2 to 20% (v/v) did not reduce the RRF value for cells of the wild-type strains: wt1 , wt2 or the Δ sod2 mutant

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Therefore the hippocampal lesion observed in this study (Figure 17) might be responsible for the impairment in memory and learning exhibited by the rats in Group II and the protective effect of DMSO may perhaps be responsible for the enhancement of learning and memory observed in Group I