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During early neurogenesis in the retina of embryonic chickens, an agonist of GABA B blocked Ca 2+ signaling during retinal Ca 2+ waves, while the GABA B antagonist p-3-aminopropyl-p-dietoxymethyl phosphoric acid increased the duration of the transient, illustrating that the GABA receptor subtype plays a crucial role in regulating Ca 2+ waves prior to synapse formation [112]
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