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Under 13 C 3 -serine tracing, isotope-labeled cystathionine and cysteine were significantly increased after DMF treatment (Fig

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For example, the reduction of pyruvate to lactate, as catalyzed by lactate dehydrogenase, is accompanied by the oxidation of NADH to NAD + , as shown in the following two half-reactions: To evaluate the driving force for the full reaction to occur, one would consider the standard reduction potential, E°, associated with each of the individual half reactions