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The BUD is set by the pharmacy and reflects how long the compounded medication is guaranteed to remain safe and effective

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One study has shown that patients should be referred when their serum bilirubin level reaches to 100 μ mol/l (5.9 mg/dl) and that the outcome post transplantation is better than without transplantation when the serum bilirubin level is less than 170 μ mol/l (10 mg/dl) [128]