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Gruetter and Tkác, 2000) was used for shimming, leading to water linewidths of 9–10 Hz in the hippocampus and of 18–20 Hz for the dMRS VOI (Figure 1A)

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An approximation for this value in “unperturbed” Cys residues in proteins is ~8.5 [29] (depending on multiple factors including dielectric constant), but reactive Cys often exhibit lowered p K a values as a result of a protein environment that stabilizes the negatively-charged thiolate anion (e.g