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For example, the TfR1 inhibitor Ferstatin II significantly suppresses TfR1 activity in vitro and in vivo , improving cartilage degradation

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A dense band-like lymphohistiocytic infiltrate along the dermal–epidermal junction, with patchy-to-florid vacuolar interface dermatitis and basilar/suprabasilar apoptotic keratinocytes compose the histopathologic pattern of CPI-mediated lichenoid rash [10]