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Cyanocobalamin injections are often prescribed to gastric bypass patients who have had part of their small intestine bypassed, making it difficult for B 12 to be acquired via food or vitamins

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Research protocols using 5-Amino-1MQ typically administer 50–100mg daily via subcutaneous injection, based on human equivalent dose scaling from rodent studies where 10mg/kg bodyweight produced measurable NNMT suppression and increased NAD+ bioavailability