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Although the differences did not reach statistical significance, CAT and GSH-Px activities were also elevated in the HLG group relative to the HLA group

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Discussion Through the use of Nrf2-disrupted models (cells and mice), our laboratory and others have previously reported that Nrf2 protects from cell death induced by multiple oxidants (H 2 O 2 , tBHQ, cigarette smoke, hyperoxia, and anticancer drugs) mainly by alleviating cellular ROS levels [17]