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In humans, intravenous infusion of PP (10 pmol/kg/min) (supra-physiological levels of PP) in ten healthy volunteers (men and women of normal body weight) caused a sustained decrease in both appetite and cumulative 24-hour energy intake by 25.3 +/- 5.8% (193)

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To further support our findings of increased Lm changes in the 15 days BSO/CS group, 2 protease markers of elastase and MMP activity were measured