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A separate 2025 narrative review searching multiple databases through March of that year identified only three small human pilot studies involving BPC-157: one on intra-articular knee pain, one on interstitial cystitis, and one examining intravenous safety and pharmacokinetics

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Natural mitochondrial-targeting drugs with antioxidant properties are effective methods to prevent and treat UV-induced skin damage by reducing mitochondrial oxidative stress [55]