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2: Transplant and Cellular Therapies - Clinical P280 EXPERIENCE OF MISMATCHED UNRELATED DONOR TRANSPLANTS WITH PTCY BASED GVHD PROPHYLAXIS IN BENIGN HEMATOLOGICAL DISORDERS Akanksha Garg 1 , Nidhi Jain 1 , Rajan Yadav 2 1 Zydus Cancer Hospital, Ahmedabad, India, 2 Gujarat Cancer and Research Institute, Ahmedabad, India Background : Allogeneic hematopoietic stem cell transplantation (allo-HSCT) from mismatched unrelated donors (MMUD) is an option for patients with benign hematological disorders (e.g., aplastic anemia, hemoglobinopathies, inherited bone marrow failure syndromes and inborn errors of immunity) who lack matched sibling donors
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One important limitation is that these dosing approaches are largely anecdotal and not derived from controlled psychiatric research