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After the peroxidation compounds are formed, H 2 O 2 can then diffuse into immune cells and regulate signal transduction, stimulate cellular/humoral immunity/phagocytic function and immune responses such as reduction of cytokines (interleukin-1, interleukin-6, tumor necrosis factor-α, and interleukin-10 etc.), induction of interferon-γ, and others

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In addition, the gut microbiota was found to influence the process of monocyte migration from the periphery to the brain mediated by TNF-α, which was reversed by the use of probiotics (119)