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Patients received either pemetrexed 500 mg/m2 intravenously in combination with cisplatin 75 mg/m2 intravenously on Day 1 of each 21-day cycle (n=839) or gemcitabine 1250 mg/m2 intravenously on Days 1 and 8 in combination with cisplatin 75 mg/m2 intravenously on Day 1 of each 21-day cycle (n=830)