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Discussion: In conclusion, CMP ameliorates systemic chronic inflammation in T2DM by disrupting the ROS–M1 macrophage vicious cycle

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In this article, we summarize the regulation mechanism of melanogenesis and review existing cases of hair repigmentation caused by several factors, including monoclonal antibodies drugs, tyrosine kinase inhibitors (TKIs), immunomodulators, other drugs, micro-injury, and tumors, and speculate on the mechanisms behind them