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Benefits (Research Focus) β’ NNMT inhibition β studied as a selective small-molecule inhibitor of nicotinamide N-methyltransferase β’ NAD+ preservation β investigated for preservation of cellular NAD+ pools and downstream sirtuin pathway activity β’ Adipose tissue research β explored for lipolysis markers and fat-mass partitioning in DIO rodent models β’ Skeletal muscle metabolism β examined for endpoints related to muscle aging and sarcopenia models β’ Metabolic signaling β researched for glucose homeostasis and insulin sensitivity endpoints in metabolic disease models What Researchers Look At β’ NNMT enzymatic activity and 1-methylnicotinamide (1-MNA) tissue concentrations β’ Intracellular NAD+ / NADH ratio and downstream sirtuin (SIRT1/SIRT3) activation β’ Body composition, fat mass, and lean mass partitioning in DIO rodent models β’ Adipocyte lipolysis markers and adipose tissue inflammation profiles β’ Glucose tolerance, insulin sensitivity, and hepatic steatosis endpoints Quick Specs β’ Form: Lyophilized white powder β’ Net Content: 50 mg per vial (as iodide salt) β’ Quantity: 1 vial β’ Appearance: White to off-white lyophilizate β’ Reconstitution: Bacteriostatic or sterile water (added by the end researcher) β’ Purity: β₯99% by HPLC β’ Identity: MS-verified (per COA) β’ Storage: Protect from light Identity Basics β’ Compound: 5-Amino-1MQ (5-Amino-1-methylquinolinium iodide) β’ Synonyms: 5-Amino-1-methylquinolinium
