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However, some individuals report experiences that suggest possible associations between B12 and anxiety-like symptoms in certain contexts: High-dose supplementation : Some individuals report feeling 'overstimulated' or experiencing changes in energy levels when initiating B12 supplements

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Side Effects of Excessive B12 Intake Whilst vitamin B12 toxicity is uncommon, several adverse effects have been reported in association with very high B12 levels, though establishing direct causation remains challenging