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Finally, as the goal of fluorescence-guided surgery is to improve patient survival, future studies are needed to determine whether resection of additional lesions by fluorescence imaging improves long-term prognosis

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Copper may influence the expression of Aβ degrading enzymes such as neprilysin (NEP) and insulin-degrading enzyme (IDE), leading to insufficient Aβ clearance, which in turn affects decision-making, planning, and executive functions (76)