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The gut microbiota produces its own antigens through protein post-translational modifications, activates Toll-like receptor 4 induced by lipopolysaccharide (LPS), induces T helper cell translocation from type 1 (Th1) to type 2 (Th2), reduces the integrity of intercellular connections, and promotes AITD development through intestinal leakage (Lerner et al., 2017)
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This decreased threshold was significantly attenuated in the BPC10, BPC20, BPC40 and morphine groups at the same time
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