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In a single-center, phase 2, double-blind, placebo-controlled study patients received VR040 at three different doses (0.2, 0.5, and 0.8 mg)
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However, at higher concentrations, a reverse trend may occur due to an overload or saturation effect of the molecules in the ethanol extract, resulting in pro-oxidant activity and declining effects
![A schematic overview of RBC metabolism [3,9,14,15,16,17,18,19,20,21]](https://www.researchgate.net/publication/375624019/figure/fig1/AS:11431281420371687@1746247523956/A-schematic-overview-of-RBC-metabolism-3-9-14-15-16-17-18-19-20-21-Each-box-provides-a_Q320.jpg)
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