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The compound sits at a low evidence tier — there is a reasonable preclinical base and some early human data suggesting a fat-loss signal, but that is a very different thing from established clinical efficacy

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Thus, the present review is aimed to provide an insight into the recent progression in the molecular mechanisms targeting dysregulated immune response and cellular dysfunction involved in the development of sepsis-associated AKI, accentuating the phytoconstituents as eligible candidates for attenuating the onset and progression of sepsis-associated AKI

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