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Second, existing biomarkers have not been adjusted for age differences between pediatric and adult TBI patients, leading to high false-positive rates for children in multicenter cohorts
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HIV-infected leukocytes can then infect the healthy brain that would have been otherwise blocked by the BBB and begin to directly cause neuronal dysfunction by inducing chronic inflammation or neuronal degeneration via Gp120, Tat, and VPR proteins [4]
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