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4.2 Activation of the NLRP3 inflammasome and maturation/release of IL-1β MSU crystals act as the central initiators of tophus formation by activating the NLRP3 inflammasome and inducing the maturation and release of IL-1β through a tightly regulated two-step signaling process
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[DOI] [PubMed] [Google Scholar] 37.Tran V., De Silva T.M., Sobey C.G., Lim K., Drummond G.R., Vinh A., Jelinic M
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