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Oral Pinealon is the route used in the small published human reports from the Khavinson group, including a 72-patient study in adults with consequences of traumatic brain injury and cerebrasthenia

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In other words, mGSTA4 knockouts in the C57BL background do not accumulate fat not because they fail to respond to 4HNE, but because they do not have more 4HNE in the first place

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