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It has a crucial role in regulating mitochondrial metabolism, primarily by inhibiting succinate dehydrogenase (SDH), hence diminishing the generation of reactive oxygen species (ROS)

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The Dominant Role of Sp1 in Regulating the Cystathionine β-Synthase -1a and -1b Promoters Facilitates Potential Tissue-specific Regulation by Kruppel-like Factors