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Based on results from the PIONEER project, oral semaglutide has been approved for treatment in patients with type 2 diabetes, where a 14 mg dose can reduce hemoglobin A1c (HbA1c) levels by up to −1.4% and lead to a weight loss of up to 4.4 kg

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Patients with selective reactions to AX are defined as those with negative skin test to BP determinants but positive to AX, with good tolerance to BP and penicillin V, and sIgE antibodies to AX but no detection of sIgE to BP