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Lenti et al said it well: “Patients with unexplained iron deficiency anemia or those with refractory iron deficiency anemia (that is, those who do not respond to iron supplementation) should be investigated for AIG [AAG]” 1 Jan 13 2025 Vitamin B12 Deficiency in Patients with Iron Deficiency Autoimmune atrophic gastritis (AAG) leads to hypochlorhydria or achlorhydria due to destruction of parietal cells in the gastric body, potentially interfering with absorption of oral iron and subsequent IDA