gcl glutathione Schematic overview of (GSH) metabolism and the targeting sites of inhibitors. Color codes are defined as follows: black = enzymes or transporters; red = metabolites; blue = inhibitors. GGT: γ-glutamyl transferase Option:2-pack (1 pink/1 gray) Reclaim Ag | Order Healthy Aging

gcl glutathione Schematic overview of (GSH) metabolism and the targeting sites of inhibitors. Color codes are defined as follows: black = enzymes or transporters; red = metabolites; blue = inhibitors. GGT: γ-glutamyl transferase Option:2-pack (1 pink/1 gray) Reclaim Ag | Order Healthy Aging

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10.1111/1750-3841.13578 120 LindM.HayesA.CaprndaM.PetrovicD.RodrigoL.KruzliakP.et al (2017)

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Option:2-pack (1 pink/1 gray)

However, redox cycling between Cu(I) and Cu(II) can contribute to the catalytic generation of highly toxic hydroxyl radicals, subsequently damaging macromolecules (Halliwell and Gutteridge, 1984)