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Finally, Table 5 illustrates that 12 cellular ribosomal proteins were clearly down-regulated, between 1.8- and 9-fold, which may drive a severe decrease in cellular protein synthesis, due to mitochondrial energy deficits, resulting in a relatively quiescent metabolic phenotype

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This is essential in figuring out whether you should be taking B12 injections to reduce symptoms and avoid vitamin B12 deficiency that can be debilitating